Tissue Transglutaminase

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The Tissue Transglutaminase testing is used to help diagnose the presence of Coeliac Disease.  Tissue transglutaminase is an IgA enzyme that fixes damage in the body.  This enzyme is usually present in patients with Coeliac disease.  The antibodies that attack these enzymes are called anti-tissue Transglutaminase antibodies.  A blood test that indicates increased levels of these antibodies can help a practitioner to determine the presence of Coeliac Disease.

Test results may vary depending on health history, gender and age.  The higher levels of Tissue Transglutaminase  antibodies in your blood, the increase likelihood of a related inflammatory disorder.  In younger children, tissue transglutaminase antibodies may not appear in increased levels in children with Coeliac disease.  This may be due to lack of established immunity.

This test can be utilized in patients with increased risk of disease (previous diagnosis with associated disorder, family history, positive for HLA DQ2 and/or DQ8).  Coeliac disease is an autoimmune disorder of the small bowel characterized by mucosal inflammation, villous atrophy and crypt hyperplasia which occurs upon exposure to dietary gluten.  Gluten is a protein found in foods such as wheat, barley, rye and oats.  Coeliac disease usually presents with gastrointestinal symptoms such as diarrhea, malabsorption, or weight loss.

Specimen Requirements

One blood sample is required for completion of test.  Take a referral along to the nearest Australian Clinical Labs collection centre.  Find your nearest collection centre by going online at clinicallabs.com.au/location.

Patient Preparation

Patient does not need to fast or make any special preparation before having blood collected.

Turnaround Time

The standard turnaround time for this test is 5 – 7 business days.

Price

$30.15

Additional $20.00 collection fee applies to this test.

Code

TTG

Test Results

Patient results are delivered to the referring practitioner via electronic download unless requested otherwise. Results can also be issued via hardcopy or fax.

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    Terms and Conditions of Service

    It is your responsibility to ensure you carefully follow all steps provided to ensure the health and safety of the couriers, postage workers, specimen reception and laboratory workers.

    There is no rebate offered through the Medicare Benefits Scheme for the kits available on the Australian Clinical Labs shopping cart. Some private health insurance companies may offer rebates, check with your health insurance provider for further details.

    You are responsible for selection the correct test through the online shopping portal, if you are unsure, confirm with your referring practitioner. If your kit arrives through the mail damaged, contact us immediately for a replacement – do not use or send back this kit.

    Australian Clinical Labs does issue refunds to unused tests for up to 6 months from purchase date, a cancellation fee of $30 applies to all kits. We do not issue refunds for kits purchased over 6 months prior to the refund request.

    All kits to be returned are to have the referral form included with the samples. Without this form, there will be no patient allocated to the results and the test will take longer to process.