Osteoporosis affects over 75 million men and women worldwide and places 1 out of every 2 women at the risk of developing bone fractures. Unfortunately the degenerative disease is often not detected until it is well advanced and a bone fracture (most commonly the hip) is usually one of the first symptoms. Early detection of osteoporosis can help to facilitate successful treatment and reduce the risk of further advancement of the disease.
The Osteoporosis Risk Assessment (NTx) is a urine test which measures the risk of osteoporosis by detecting the rate of bone resorption (breakdown) well before significant changes are obvious on bone mineral density scans. Research indicates that elevated bone resorption is the primary cause of age-related bone loss and low bone mass is the major cause of osteoporosis.
Once osteoporosis has been diagnosed, quantitative measures of the excretion of cross-linked N-telopeptide (NTx), type 1 bone collagen, provide an indicator of human bone resorption.
The NTx marker can also be used to monitor the efficacy of anti-resorptive therapies such as hormone replacement (HRT) and/or calcium supplementation in postmenopausal women, individuals with osteoporosis and those with Paget's disease.
Once the practitioner has given the patient their request form the patient can order their test kit online at www.befunctional.com.au or by calling BeFunctional Labs customer service on 1300 55 44 80 between the hours of 9:00am and 5:00pm AEST. The test kit contains full instructions.
One urine specimen collected from the second morning void (the second urine after waking in the morning). The test kit provided contains everything required to complete the test.
- It is recommended the patient does not engage in excessive exercise the day before the test.
- Follow normal diet the day before the test.
- Fasting from 10:00pm the night before collection.
The standard turnaround time for this test is 10 – 14 working days from the date the patient’s specimen/s are received by our laboratory.
Patient results are delivered to the referring practitioner via electronic download unless requested otherwise. Results can also be issued via hardcopy, fax or web based e-viewer.
- Baseline Hormone Profile
- Adrenal Hormone Profile
The results of the Osteoporosis Risk Assessment may be further supported by additional BeFunctional testing. For example, the Baseline Hormone Profile may provide important information on hormonal imbalance and alert the practitioner to this additional risk in the development of osteoporosis.
Prolonged stress may also constitute a risk in the development and progression of osteoporosis. The Adrenal Hormone Profile, which measures Cortisol and DHEA-S over a 24-hour period may therefore be a useful adjunct to the Osteoporosis Risk Assessment.