The myDNA test is a test that analyses the DNA of an individual patient and Pharmacogenomics. The myDNA test is the study of how genetic factors may influence an individual’s response to certain medications. myDNA test combines the study of pharmacology (the study of how drugs work in the body) and genomics (the study of genes and their functions). myDNA test is a reliable way of assisting practitioners in selecting safe and effective medications for their patients based on each patient's unique genetic makeup.
There are certain genes which contain instructions to build enzymes which, in turn, helps the body to break down medications, primarily in the liver. Every individual’s genetic makeup comprises of variations of each of these protein producing genes. Each gene will also present varying levels of activity (e.g. slow, normal or fast), and as a result, individuals vary in how slow or fast they break down and clear medications from their body. This test can aid in the clinical understanding of a patients predisposition to metabolize. This test can help to pinpoint areas in phase I detoxification that may need support.
Test Kit/Specimen Collection
Buccal swab – Once the practitioner has given the patient their request form, the patient can order their test kit online at befunctional.com.au/store.
Blood - Once the practitioner has given the patient their request form, the patient takes it to their nearest Clinical Labs pathology collection centre. Please call 1300 55 44 80 or visit clinicallabs.com.au/location for a list of collection centres. Note that the blood specimen can be taken at any time of day and fasting is not required beforehand.
The myDNA test is suitable for children.
This test can be performed on either a blood specimen or buccal (cheek cell) swab.
- Patients must list any current medications on their referral form but are not required to discontinue any medications
- Avoid eating or drinking anything at least 30 minutes prior to collection of swab sample
- Fasting is not required for the blood sample
The standard turnaround time for this test is 10-14 business days.
Additional $20.00 postage & handling OR collection fee applies to this test.
Blood: No prepayment is required. Patient will be billed once the testing is completed.
Swab: Prepayment is required when ordering kit.
- MTHFR Gene Test
- Urinary Pyrrole Testing
The results of an MTHFR test in relation to a myDNA test can help to determine whether inhibited methylation may be influencing phase I detoxification. Mutations in the C677T and A1298C SNPs (Single Nucleotide Polymorphisms) affect the methylation and the conversion of homocysteine into methionine as well as the breakdown of heavy metals. Assessing the capability of MTHFR SNPs and SNPs assessed in the myDNA test can evaluate whether a patient has significantly inhibited metabolization.
Pyroluria increases the depletion of key nutrients needed for neurotransmitter production, tissue repair/immune response and liver detoxification. The deficiency of these key nutrients can specifically effect enzyme function in phase I metabolization. This can alter the patient's ability to metabolize pharmaceuticals, toxins and chemicals in our environment.